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The p75 Neurotrophin Receptor Is Required for the Major Loss of Sympathetic Nerves From Islets Under Autoimmune Attack

Our goal was to determine the role of the p75 neurotrophin receptor (p75NTR) in the loss of islet sympathetic nerves that occurs during the autoimmune attack of the islet. The islets of transgenic (Tg) mice in which β-cells express a viral glycoprotein (GP) under the control of the insulin promotor...

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Detalles Bibliográficos
Autores principales: Taborsky, Gerald J., Mei, Qi, Bornfeldt, Karin E., Hackney, Daryl J., Mundinger, Thomas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066345/
https://www.ncbi.nlm.nih.gov/pubmed/24608438
http://dx.doi.org/10.2337/db13-0778