PKR is activated by cellular dsRNAs during mitosis and acts as a mitotic regulator

dsRNA-dependent protein kinase R (PKR) is a ubiquitously expressed enzyme well known for its roles in immune response. Upon binding to viral dsRNA, PKR undergoes autophosphorylation, and the phosphorylated PKR (pPKR) regulates translation and multiple signaling pathways in infected cells. Here, we f...

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Detalles Bibliográficos
Autores principales: Kim, Yoosik, Lee, Jung Hyun, Park, Jong-Eun, Cho, Jun, Yi, Hyerim, Kim, V. Narry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066401/
https://www.ncbi.nlm.nih.gov/pubmed/24939934
http://dx.doi.org/10.1101/gad.242644.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066401/
https://www.ncbi.nlm.nih.gov/pubmed/24939934
http://dx.doi.org/10.1101/gad.242644.114

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