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Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia

Microglia are myeloid cells of the central nervous system (CNS) that participate both in normal CNS function and disease. We investigated the molecular signature of microglia and identified 239 genes and 8 microRNAs that were uniquely or highly expressed in microglia vs. myeloid and other immune cel...

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Detalles Bibliográficos
Autores principales: Butovsky, Oleg, Jedrychowski, Mark P., Moore, Craig S., Cialic, Ron, Lanser, Amanda J., Gabriely, Galina, Koeglsperger, Thomas, Dake, Ben, Wu, Pauline M., Doykan, Camille E., Fanek, Zain, Liu, LiPing, Chen, Zhuoxun, Rothstein, Jeffrey D., Ransohoff, Richard M., Gygi, Steven P., Antel, Jack P., Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066672/
https://www.ncbi.nlm.nih.gov/pubmed/24316888
http://dx.doi.org/10.1038/nn.3599