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Robustly detecting differential expression in RNA sequencing data using observation weights

A popular approach for comparing gene expression levels between (replicated) conditions of RNA sequencing data relies on counting reads that map to features of interest. Within such count-based methods, many flexible and advanced statistical approaches now exist and offer the ability to adjust for c...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaobei, Lindsay, Helen, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066750/
https://www.ncbi.nlm.nih.gov/pubmed/24753412
http://dx.doi.org/10.1093/nar/gku310