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The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification
The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator, contributes to many of the identified control mechanisms, including the regulation of chromatin, RNA polymerases, and RNA processing. Moreover, MYC recr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066752/ https://www.ncbi.nlm.nih.gov/pubmed/24782528 http://dx.doi.org/10.1093/nar/gku312 |