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Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domain

The tandem repeats of transcription activator like effectors (TALEs) mediate sequence-specific DNA binding using a simple code. Naturally, TALEs are injected by Xanthomonas bacteria into plant cells to manipulate the host transcriptome. In the laboratory TALE DNA binding domains are reprogrammed and...

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Detalles Bibliográficos
Autores principales: de Lange, Orlando, Wolf, Christina, Dietze, Jörn, Elsaesser, Janett, Morbitzer, Robert, Lahaye, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066763/
https://www.ncbi.nlm.nih.gov/pubmed/24792163
http://dx.doi.org/10.1093/nar/gku329