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HIV-1 DIS stem loop forms an obligatory bent kissing intermediate in the dimerization pathway

The HIV-1 dimerization initiation sequence (DIS) is a conserved palindrome in the apical loop of a conserved hairpin motif in the 5′-untranslated region of its RNA genome. DIS hairpin plays an important role in genome dimerization by forming a ‘kissing complex’ between two complementary hairpins. Un...

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Detalles Bibliográficos
Autores principales: Mundigala, Hansini, Michaux, Jonathan B., Feig, Andrew L., Ennifar, Eric, Rueda, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066764/
https://www.ncbi.nlm.nih.gov/pubmed/24813449
http://dx.doi.org/10.1093/nar/gku332