Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition

It is a central issue to elucidate the new type of molecular recognition accompanied by a global structural change of a molecule upon binding to its targets. Here we investigate the driving force for the binding of R12 (a ribonucleic acid aptamer) and P16 (a partial peptide of a prion protein) durin...

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Detalles Bibliográficos
Autores principales: Hayashi, Tomohiko, Oshima, Hiraku, Mashima, Tsukasa, Nagata, Takashi, Katahira, Masato, Kinoshita, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066790/
https://www.ncbi.nlm.nih.gov/pubmed/24803670
http://dx.doi.org/10.1093/nar/gku382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066790/
https://www.ncbi.nlm.nih.gov/pubmed/24803670
http://dx.doi.org/10.1093/nar/gku382

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