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Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition
It is a central issue to elucidate the new type of molecular recognition accompanied by a global structural change of a molecule upon binding to its targets. Here we investigate the driving force for the binding of R12 (a ribonucleic acid aptamer) and P16 (a partial peptide of a prion protein) durin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066790/ https://www.ncbi.nlm.nih.gov/pubmed/24803670 http://dx.doi.org/10.1093/nar/gku382 |