Cargando…

Haloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation

The prokaryotic immune system CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated genes) adapts to foreign invaders by acquiring their short deoxyribonucleic acid (DNA) fragments as spacers, which guide subsequent interference to foreign nucleic acids based on seq...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ming, Wang, Rui, Xiang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066796/
https://www.ncbi.nlm.nih.gov/pubmed/24803673
http://dx.doi.org/10.1093/nar/gku389