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Haloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation
The prokaryotic immune system CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated genes) adapts to foreign invaders by acquiring their short deoxyribonucleic acid (DNA) fragments as spacers, which guide subsequent interference to foreign nucleic acids based on seq...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066796/ https://www.ncbi.nlm.nih.gov/pubmed/24803673 http://dx.doi.org/10.1093/nar/gku389 |