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Nascent RNA transcripts facilitate the formation of G-quadruplexes

Recent discovery of the RNA/DNA hybrid G-quadruplexes (HQs) and their potential wide-spread occurrence in human genome during transcription have suggested a new and generic transcriptional control mechanism. The G-rich sequence in which HQ may form can coincide with that for DNA G-quadruplexes (GQs)...

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Detalles Bibliográficos
Autores principales: Shrestha, Prakash, Xiao, Shan, Dhakal, Soma, Tan, Zheng, Mao, Hanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066803/
https://www.ncbi.nlm.nih.gov/pubmed/24829453
http://dx.doi.org/10.1093/nar/gku416