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Hydrolytic function of Exo1 in mammalian mismatch repair

Genetic and biochemical studies have previously implicated exonuclease 1 (Exo1) in yeast and mammalian mismatch repair, with results suggesting that function of the protein in the reaction depends on both its hydrolytic activity and its ability to interact with other components of the repair system....

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Detalles Bibliográficos
Autores principales: Shao, Hongbing, Baitinger, Celia, Soderblom, Erik J., Burdett, Vickers, Modrich, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066806/
https://www.ncbi.nlm.nih.gov/pubmed/24829455
http://dx.doi.org/10.1093/nar/gku420