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Macrophage activation state determines the response to rhinovirus infection in a mouse model of allergic asthma

BACKGROUND: The mechanisms by which viruses cause asthma exacerbations are not precisely known. Previously, we showed that, in ovalbumin (OVA)-sensitized and -challenged mice with allergic airway inflammation, rhinovirus (RV) infection increases type 2 cytokine production from alternatively-activate...

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Detalles Bibliográficos
Autores principales: Hong, Jun Young, Chung, Yutein, Steenrod, Jessica, Chen, Qiang, Lei, Jing, Comstock, Adam T, Goldsmith, Adam M, Bentley, J Kelley, Sajjan, Uma S, Hershenson, Marc B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066837/
https://www.ncbi.nlm.nih.gov/pubmed/24907978
http://dx.doi.org/10.1186/1465-9921-15-63