Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice

Objectives. The role of the NLRP3 inflammasome in atherosclerosis remains controversial. The aim of this study was to determine whether inhibition of NLRP3 signaling by lentivirus-mediated RNA interference could reduce atherosclerosis and stabilizes plaques. We also tried to explore the mechanisms o...

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Detalles Bibliográficos
Autores principales: Zheng, Fei, Xing, Shanshan, Gong, Zushun, Mu, Wei, Xing, Qichong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066943/
https://www.ncbi.nlm.nih.gov/pubmed/24999295
http://dx.doi.org/10.1155/2014/507208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066943/
https://www.ncbi.nlm.nih.gov/pubmed/24999295
http://dx.doi.org/10.1155/2014/507208

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