B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk

Binding of antigen to the B cell antigen receptor (BCR) initiates a multitude of events resulting in B cell activation. How the BCR becomes signaling-competent upon antigen binding is still a matter of controversy. Using a high-resolution proximity ligation assay (PLA) to monitor the conformation of...

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Detalles Bibliográficos
Autores principales: Kläsener, Kathrin, Maity, Palash C, Hobeika, Elias, Yang, Jianying, Reth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067077/
https://www.ncbi.nlm.nih.gov/pubmed/24963139
http://dx.doi.org/10.7554/eLife.02069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067077/
https://www.ncbi.nlm.nih.gov/pubmed/24963139
http://dx.doi.org/10.7554/eLife.02069

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