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Binding Affinity and Cooperativity Control U2B″/snRNA/U2A′ RNP Formation

[Image: see text] The U1A and U2B″ proteins are components of the U1 and U2 snRNPs, respectively, where they bind to snRNA stemloops. While localization of U1A and U2B″ to their respective snRNP is a well-known phenomenon, binding of U2B″ to U2 snRNA is typically thought to be accompanied by the U2A...

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Detalles Bibliográficos
Autores principales: Williams, Sandra G., Hall, Kathleen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067145/
https://www.ncbi.nlm.nih.gov/pubmed/24866816
http://dx.doi.org/10.1021/bi500438e