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Bet v 1 from Birch Pollen Is a Lipocalin-like Protein Acting as Allergen Only When Devoid of Iron by Promoting Th2 Lymphocytes

It is hypothesized that allergens are at the borderline of self and non-self and, through as yet elusive circumstances, mount a Th2 response for allergic sensitization. The major birch pollen allergen Bet v 1 is considered the prototype for the PR-10 protein family causing respiratory allergy. Here,...

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Detalles Bibliográficos
Autores principales: Roth-Walter, Franziska, Gomez-Casado, Cristina, Pacios, Luis F., Mothes-Luksch, Nadine, Roth, Georg A., Singer, Josef, Diaz-Perales, Araceli, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067174/
https://www.ncbi.nlm.nih.gov/pubmed/24798325
http://dx.doi.org/10.1074/jbc.M114.567875