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β1-adrenergic receptor stimulation by agonist Compound 49b restores insulin receptor signal transduction in vivo

PURPOSE: Determine whether Compound 49b treatment ameliorates retinal changes due to the lack of β2-adrenergic receptor signaling. METHODS: Using retinas from 3-month-old β2-adrenergic receptor-deficient mice, we treated mice with our novel β1-/β2-adrenergic receptor agonist, Compound 49b, to assess...

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Detalles Bibliográficos
Autores principales: Jiang, Youde, Zhang, Qiuhua, Ye, Eun-Ah, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067233/
https://www.ncbi.nlm.nih.gov/pubmed/24966659