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Synthesis of 3,3′-Di-O-methyl Ardimerin and Exploration of Its DNA Binding Properties
[Image: see text] The 3,3′-di-O-methyl derivative (15) of the bis-C-aryl glycoside natural product ardimerin (1) has been synthesized in 11 steps from 2,3,4,6-tetrabenzylglucose (2) and 1,2,3-trimethoxybenzene (3). Key steps in the synthesis involve a Lewis acid mediated Friedel–Crafts type glycosyl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067242/ https://www.ncbi.nlm.nih.gov/pubmed/24712737 http://dx.doi.org/10.1021/ol500725e |