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Synthesis of 3,3′-Di-O-methyl Ardimerin and Exploration of Its DNA Binding Properties

[Image: see text] The 3,3′-di-O-methyl derivative (15) of the bis-C-aryl glycoside natural product ardimerin (1) has been synthesized in 11 steps from 2,3,4,6-tetrabenzylglucose (2) and 1,2,3-trimethoxybenzene (3). Key steps in the synthesis involve a Lewis acid mediated Friedel–Crafts type glycosyl...

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Detalles Bibliográficos
Autores principales:	Mavlan, Miran, Ng, Kevin, Panesar, Harmanpreet, Yepremyan, Akop, Minehan, Thomas G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067242/ https://www.ncbi.nlm.nih.gov/pubmed/24712737 http://dx.doi.org/10.1021/ol500725e

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