Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension

Mutations affecting transforming growth factor-beta (TGF-β) superfamily receptors, activin receptor-like kinase (ALK)-1, and endoglin (ENG) occur in patients with pulmonary arterial hypertension (PAH). To determine whether the TGF-β/ALK1/ENG pathway was involved in PAH, we investigated pulmonary TGF...

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Detalles Bibliográficos
Autores principales: Gore, Benoît, Izikki, Mohamed, Mercier, Olaf, Dewachter, Laurence, Fadel, Elie, Humbert, Marc, Dartevelle, Philippe, Simonneau, Gerald, Naeije, Robert, Lebrin, Franck, Eddahibi, Saadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067299/
https://www.ncbi.nlm.nih.gov/pubmed/24956016
http://dx.doi.org/10.1371/journal.pone.0100310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067299/
https://www.ncbi.nlm.nih.gov/pubmed/24956016
http://dx.doi.org/10.1371/journal.pone.0100310

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