Deficiency of Formyl Peptide Receptor 1 and 2 Is Associated with Increased Inflammation and Enhanced Liver Injury after LPS-Stimulation

INTRODUCTION: Formyl peptide-receptor 1 and 2 (FPR1 and FPR2) in mice were identified as receptors with contrary affinity for the PAMP fMLF. Formyl-methionyl-leucyl-phenylalanine is either part of the bacterial membrane and is secreted by the mitochondria of eukaryotic ceslls during apoptosis. Furth...

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Detalles Bibliográficos
Autores principales: Giebeler, Arne, Streetz, Konrad L., Soehnlein, Oliver, Neumann, Ulf, Wang, Ji Ming, Brandenburg, Lars-Ove
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067326/
https://www.ncbi.nlm.nih.gov/pubmed/24956481
http://dx.doi.org/10.1371/journal.pone.0100522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067326/
https://www.ncbi.nlm.nih.gov/pubmed/24956481
http://dx.doi.org/10.1371/journal.pone.0100522

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