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HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains

The retroviral oncoprotein Tax from Human T cell leukemia virus type 1 (HTLV-1), an etiological factor that causes adult T cell leukemia and lymphoma, plays a crucial role in initiating T lymphocyte transformation by inducing oncogenic signaling activation. We here report that Tax is a determining f...

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Detalles Bibliográficos
Autores principales: Ren, Tong, Takahashi, Yoshinori, Liu, Xin, Loughran, Thomas P., Sun, Shao-Cong, Wang, Hong-Gang, Cheng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067462/
https://www.ncbi.nlm.nih.gov/pubmed/24362528
http://dx.doi.org/10.1038/onc.2013.552