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TRAF2 is an NF-κB activating oncogene in epithelial cancers

Aberrant NF-κB activation is frequently observed in human cancers. Genome characterization efforts have identified genetic alterations in multiple components of the NF-κB pathway, some of which have been shown to be essential for cancer initiation and tumor maintenance. Here using patient tumors and...

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Detalles Bibliográficos
Autores principales: Shen, Rhine R., Zhou, Alicia Y., Kim, Eejung, O’Connell, Joyce T., Hagerstrand, Daniel, Beroukhim, Rameen, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067463/
https://www.ncbi.nlm.nih.gov/pubmed/24362534
http://dx.doi.org/10.1038/onc.2013.543