p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes

The p53 tumor suppressor protein is a major sensor of cellular stresses, and upon stabilization, activates or represses many genes that control cell fate decisions. While the mechanism of p53-mediated transactivation is well established, several mechanisms have been proposed for p53-mediated repress...

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Detalles Bibliográficos
Autores principales: Benson, E K, Mungamuri, S K, Attie, O, Kracikova, M, Sachidanandam, R, Manfredi, J J, Aaronson, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067464/
https://www.ncbi.nlm.nih.gov/pubmed/24096481
http://dx.doi.org/10.1038/onc.2013.378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067464/
https://www.ncbi.nlm.nih.gov/pubmed/24096481
http://dx.doi.org/10.1038/onc.2013.378

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