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HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors

HER2 / Neu is amplified and overexpressed in a large proportion of human breast cancers, but the signaling pathways that contribute to tumor development and metastatic progression are not completely understood. Using gene expression data and pathway signatures we predicted a role for activator E2F t...

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Detalles Bibliográficos
Autor principal: Andrechek, Eran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067469/
https://www.ncbi.nlm.nih.gov/pubmed/24362522
http://dx.doi.org/10.1038/onc.2013.540