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PPARβ/δ activation of CD300a controls intestinal immunity

Macrophages are important for maintaining intestinal immune homeostasis. Here, we show that PPARβ/δ (peroxisome proliferator-activated receptor β/δ) directly regulates CD300a in macrophages that express the immunoreceptor tyrosine based-inhibitory motif (ITIM)-containing receptor. In mice lacking CD...

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Detalles Bibliográficos
Autores principales: Tanaka, Toshiya, Tahara-Hanaoka, Satoko, Nabekura, Tsukasa, Ikeda, Kaori, Jiang, Shuying, Tsutsumi, Shuichi, Inagaki, Takeshi, Magoori, Kenta, Higurashi, Takuma, Takahashi, Hirokazu, Tachibana, Keisuke, Tsurutani, Yuya, Raza, Sana, Anai, Motonobu, Minami, Takashi, Wada, Youichiro, Yokote, Koutaro, Doi, Takefumi, Hamakubo, Takao, Auwerx, Johan, Gonzalez, Frank J., Nakajima, Atsushi, Aburatani, Hiroyuki, Naito, Makoto, Shibuya, Akira, Kodama, Tatsuhiko, Sakai, Juro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067692/
https://www.ncbi.nlm.nih.gov/pubmed/24958459
http://dx.doi.org/10.1038/srep05412