Direct Observations of Amyloid β Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1–40) and Aβ(1–42) Aggregation

Insight into how amyloid β (Aβ) aggregation occurs in vivo is vital for understanding the molecular pathways that underlie Alzheimer’s disease and requires new techniques that provide detailed kinetic and mechanistic information. Using noninvasive fluorescence lifetime recordings, we imaged the form...

Descripción completa

Detalles Bibliográficos
Autores principales: Esbjörner, Elin K., Chan, Fiona, Rees, Eric, Erdelyi, Miklos, Luheshi, Leila M., Bertoncini, Carlos W., Kaminski, Clemens F., Dobson, Christopher M., Kaminski Schierle, Gabriele S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067742/
https://www.ncbi.nlm.nih.gov/pubmed/24856820
http://dx.doi.org/10.1016/j.chembiol.2014.03.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067742/
https://www.ncbi.nlm.nih.gov/pubmed/24856820
http://dx.doi.org/10.1016/j.chembiol.2014.03.014

Ejemplares similares