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The inhibitory microcircuit of the substantia nigra provides feedback gain control of the basal ganglia output

Dysfunction of the basal ganglia produces severe deficits in the timing, initiation, and vigor of movement. These diverse impairments suggest a control system gone awry. In engineered systems, feedback is critical for control. By contrast, models of the basal ganglia highlight feedforward circuitry...

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Detalles Bibliográficos
Autores principales: Brown, Jennifer, Pan, Wei-Xing, Dudman, Joshua Tate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067753/
https://www.ncbi.nlm.nih.gov/pubmed/24849626
http://dx.doi.org/10.7554/eLife.02397