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mrSNP: Software to detect SNP effects on microRNA binding

BACKGROUND: MicroRNAs (miRNAs) are short (19-23 nucleotides) non-coding RNAs that bind to sites in the 3’untranslated regions (3’UTR) of a targeted messenger RNA (mRNA). Binding leads to degradation of the transcript or blocked translation resulting in decreased expression of the targeted gene. Sing...

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Detalles Bibliográficos
Autores principales: Deveci, Mehmet, Çatalyürek, Ümit V, Toland, Amanda Ewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067983/
https://www.ncbi.nlm.nih.gov/pubmed/24629096
http://dx.doi.org/10.1186/1471-2105-15-73