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An Overview of Live Attenuated Recombinant Pseudorabies Viruses for Use as Novel Vaccines

Pseudorabies virus (PRV) is a double-stranded, DNA-based swine virus with a genome approximating 150 kb in size. PRV has many nonessential genes which can be replaced with genes encoding heterologous antigens but without deleterious effects on virus propagation. Recombinant PRVs expressing both nati...

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Detalles Bibliográficos
Autores principales: Dong, Bo, Zarlenga, Dante S., Ren, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068083/
https://www.ncbi.nlm.nih.gov/pubmed/24995348
http://dx.doi.org/10.1155/2014/824630