Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins

The regulated turnover of endoplasmic reticulum (ER)–resident membrane proteins requires their extraction from the membrane lipid bilayer and subsequent proteasome-mediated degradation. Cleavage within the transmembrane domain provides an attractive mechanism to facilitate protein dislocation but ha...

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Detalles Bibliográficos
Autores principales: Boname, Jessica M., Bloor, Stuart, Wandel, Michal P., Nathan, James A., Antrobus, Robin, Dingwell, Kevin S., Thurston, Teresa L., Smith, Duncan L., Smith, James C., Randow, Felix, Lehner, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068138/
https://www.ncbi.nlm.nih.gov/pubmed/24958774
http://dx.doi.org/10.1083/jcb.201312009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068138/
https://www.ncbi.nlm.nih.gov/pubmed/24958774
http://dx.doi.org/10.1083/jcb.201312009

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