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Global effects of the CSR-1 RNA interference pathway on transcriptional landscape

Argonaute proteins and their small RNA co-factors short interfering RNAs (siRNAs) are known to inhibit gene expression at the transcriptional and post-transcriptional levels. In Caenorhabditis elegans, the Argonaute CSR-1 binds thousands of endogenous siRNAs (endo-siRNAs) antisense to germline trans...

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Detalles Bibliográficos
Autores principales: Cecere, Germano, Hoersch, Sebastian, O’Keeffe, Sean, Sachidanandam, Ravi, Grishok, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068146/
https://www.ncbi.nlm.nih.gov/pubmed/24681887
http://dx.doi.org/10.1038/nsmb.2801