Downregulation of PPARγ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential

BACKGROUND: Human bone marrow mesenchymal stem cells (hBMSCs) are multipotent cells that can differentiate into a variety of cell types. Elevated expression of peroxisome proliferator-activated receptor-γ (PPARγ) promotes the adipogenic differentiation of hBMSCs, and reduces their osteogenic differe...

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Detalles Bibliográficos
Autores principales: Sun, Junkui, Wang, Yisheng, Li, Yuebai, Zhao, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068155/
https://www.ncbi.nlm.nih.gov/pubmed/24929254
http://dx.doi.org/10.1186/1479-5876-12-168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068155/
https://www.ncbi.nlm.nih.gov/pubmed/24929254
http://dx.doi.org/10.1186/1479-5876-12-168

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