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Downregulation of PPARγ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential

BACKGROUND: Human bone marrow mesenchymal stem cells (hBMSCs) are multipotent cells that can differentiate into a variety of cell types. Elevated expression of peroxisome proliferator-activated receptor-γ (PPARγ) promotes the adipogenic differentiation of hBMSCs, and reduces their osteogenic differe...

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Detalles Bibliográficos
Autores principales:	Sun, Junkui, Wang, Yisheng, Li, Yuebai, Zhao, Guoqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068155/ https://www.ncbi.nlm.nih.gov/pubmed/24929254 http://dx.doi.org/10.1186/1479-5876-12-168

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