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Prediction of Substrates for Glutathione Transferases by Covalent Docking

[Image: see text] Enzymes in the glutathione transferase (GST) superfamily catalyze the conjugation of glutathione (GSH) to electrophilic substrates. As a consequence they are involved in a number of key biological processes, including protection of cells against chemical damage, steroid and prostag...

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Detalles Bibliográficos
Autores principales: Dong, Guang Qiang, Calhoun, Sara, Fan, Hao, Kalyanaraman, Chakrapani, Branch, Megan C., Mashiyama, Susan T., London, Nir, Jacobson, Matthew P., Babbitt, Patricia C., Shoichet, Brian K., Armstrong, Richard N., Sali, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068255/
https://www.ncbi.nlm.nih.gov/pubmed/24802635
http://dx.doi.org/10.1021/ci5001554