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Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells

Endothelial cell (ECs) lining blood vessels express many mechanosensors, including platelet endothelial cell adhesion molecule-1 (PECAM-1), that convert mechanical force to biochemical signals. While it is accepted that mechanical stresses and the mechanical properties of ECs regulate vessel health,...

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Detalles Bibliográficos
Autores principales: Collins, Caitlin, Osborne, Lukas D., Guilluy, Christophe, Chen, Zhongming, O’Brien, E Tim, Reader, John S., Burridge, Keith, Superfine, Richard, Tzima, Ellie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068264/
https://www.ncbi.nlm.nih.gov/pubmed/24917553
http://dx.doi.org/10.1038/ncomms4984