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Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells
Endothelial cell (ECs) lining blood vessels express many mechanosensors, including platelet endothelial cell adhesion molecule-1 (PECAM-1), that convert mechanical force to biochemical signals. While it is accepted that mechanical stresses and the mechanical properties of ECs regulate vessel health,...
Autores principales: | Collins, Caitlin, Osborne, Lukas D., Guilluy, Christophe, Chen, Zhongming, O’Brien, E Tim, Reader, John S., Burridge, Keith, Superfine, Richard, Tzima, Ellie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068264/ https://www.ncbi.nlm.nih.gov/pubmed/24917553 http://dx.doi.org/10.1038/ncomms4984 |
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