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Loss of HNF6 expression correlates with human pancreatic cancer progression

Normal pancreatic epithelium progresses through various stages of pancreatic intraepithelial neoplasms (PanINs) in the development of pancreatic ductal adenocarcinoma (PDAC). Transcriptional regulation of this progression is poorly understood. In mouse, the Hnf6 transcription factor is expressed in...

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Detalles Bibliográficos
Autores principales: Pekala, Kelly R., Ma, Xidi, Kropp, Peter A., Petersen, Christine P., Hudgens, Courtney W., Chung, Christine H., Shi, Chanjuan, Merchant, Nipun, Maitra, Anirban, Means, Anna L., Gannon, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068339/
https://www.ncbi.nlm.nih.gov/pubmed/24638272
http://dx.doi.org/10.1038/labinvest.2014.47