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Colorectal polyp model established by transplacental BMP4 RNAi

Previous studies have shown that disruption of the bone morphogenetic protein (BMP) signaling pathway is an important cause of intestinal cancer in human and animal models. Thus, the purpose of this study was to construct a Balb/C model of colorectal polyps. Pregnant mice at 9.5 days gestation were...

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Detalles Bibliográficos
Autores principales: JIN, XIN, CHEN, ZHONGMEI, XIANG, LI, LUO, QING, GUO, ZHENGHUA, DING, XIONGHUI, JIN, XIANQING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068724/
https://www.ncbi.nlm.nih.gov/pubmed/24806485
http://dx.doi.org/10.3892/mmr.2014.2216