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Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia

Acute myeloid leukemia (AML) is a clinically heterogeneous disease, with 5-year disease-free survival (DFS) ranging from under 10% to over 70% for distinct groups of patients. At our institution, cytarabine, etoposide and busulfan are used in first or second remission patients treated with a 2-step...

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Detalles Bibliográficos
Autores principales: Yee, Sook Wah, Mefford, Joel A., Singh, Natasha, Percival, Mary-Elizabeth, Stecula, Adrian, Yang, Kuo, Witte, John S., Takahashi, Atsushi, Kubo, Michiaki, Matsuda, Koichi, Giacomini, Kathleen M., Andreadis, Charalambos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068832/
https://www.ncbi.nlm.nih.gov/pubmed/23677058
http://dx.doi.org/10.1038/jhg.2013.38