Anti-inflammatory loaded poly-lactic glycolic acid nanoparticle formulations to enhance myocardial gene transfer: an in-vitro assessment of a drug/gene combination therapeutic approach for direct injection

BACKGROUND: Cardiac gene therapy for heart disease is a major translational research area with potential, yet problems with safe and efficient gene transfer into cardiac muscle remain unresolved. Existing methodology to increase vector uptake include modifying the viral vector, non-viral particle en...

Descripción completa

Detalles Bibliográficos
Autores principales: Fargnoli, Anthony S, Mu, Anbin, Katz, Michael G, Williams, Richard D, Margulies, Kenneth B, Weiner, David B, Yang, Shu, Bridges, Charles R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068839/
https://www.ncbi.nlm.nih.gov/pubmed/24934216
http://dx.doi.org/10.1186/1479-5876-12-171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068839/
https://www.ncbi.nlm.nih.gov/pubmed/24934216
http://dx.doi.org/10.1186/1479-5876-12-171

Ejemplares similares