A Novel Nodal Enhancer Dependent on Pluripotency Factors and Smad2/3 Signaling Conditions a Regulatory Switch During Epiblast Maturation

During early development, modulations in the expression of Nodal, a TGFβ family member, determine the specification of embryonic and extra-embryonic cell identities. Nodal has been extensively studied in the mouse, but aspects of its early expression remain unaccounted for. We identified a conserved...

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Detalles Bibliográficos
Autores principales: Papanayotou, Costis, Benhaddou, Ataaillah, Camus, Anne, Perea-Gomez, Aitana, Jouneau, Alice, Mezger, Valérie, Langa, Francina, Ott, Sascha, Sabéran-Djoneidi, Délara, Collignon, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068991/
https://www.ncbi.nlm.nih.gov/pubmed/24960041
http://dx.doi.org/10.1371/journal.pbio.1001890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068991/
https://www.ncbi.nlm.nih.gov/pubmed/24960041
http://dx.doi.org/10.1371/journal.pbio.1001890

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