Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G(2)/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine

Evodiamine (EVO; 8,13,13b,14-tetrahydro-14-methylindolo[2′3′-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one derived from the traditional herbal medicine Evodia rutaecarpa was reported to possess anticancer activity; however, the anticancer mechanism is still unclear. In this study, we investigated the antic...

Descripción completa

Detalles Bibliográficos
Autores principales: Chien, Chih-Chiang, Wu, Ming-Shun, Shen, Shing-Chuan, Ko, Ching-Huai, Chen, Chih-Hung, Yang, Ling-Ling, Chen, Yen-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069003/
https://www.ncbi.nlm.nih.gov/pubmed/24959718
http://dx.doi.org/10.1371/journal.pone.0099729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069003/
https://www.ncbi.nlm.nih.gov/pubmed/24959718
http://dx.doi.org/10.1371/journal.pone.0099729

Ejemplares similares