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Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G(2)/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine
Evodiamine (EVO; 8,13,13b,14-tetrahydro-14-methylindolo[2′3′-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one derived from the traditional herbal medicine Evodia rutaecarpa was reported to possess anticancer activity; however, the anticancer mechanism is still unclear. In this study, we investigated the antic...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069003/ https://www.ncbi.nlm.nih.gov/pubmed/24959718 http://dx.doi.org/10.1371/journal.pone.0099729 |