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Constitutive Androstane Receptor Ligands Modulate the Anti-Tumor Efficacy of Paclitaxel in Non-Small Cell Lung Cancer Cells

BACKGROUND: Lung tumors are the leading cause of cancer deaths worldwide and paclitaxel has proven to be useful for patients with lung cancer, however, acquired resistance is a major problem. To overcome this problem, one promising option is the use of Constitutive Androstane Receptor (CAR) ligands...

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Detalles Bibliográficos
Autores principales: Fukumasu, Heidge, Rochetti, Arina L., Pires, Pedro R. L., Silva, Edson R., Mesquita, Ligia G., Strefezzi, Ricardo F., De Carvalho, Daniel D., Dagli, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069004/
https://www.ncbi.nlm.nih.gov/pubmed/24959746
http://dx.doi.org/10.1371/journal.pone.0099484