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Constitutive Androstane Receptor Ligands Modulate the Anti-Tumor Efficacy of Paclitaxel in Non-Small Cell Lung Cancer Cells
BACKGROUND: Lung tumors are the leading cause of cancer deaths worldwide and paclitaxel has proven to be useful for patients with lung cancer, however, acquired resistance is a major problem. To overcome this problem, one promising option is the use of Constitutive Androstane Receptor (CAR) ligands...
Autores principales: | Fukumasu, Heidge, Rochetti, Arina L., Pires, Pedro R. L., Silva, Edson R., Mesquita, Ligia G., Strefezzi, Ricardo F., De Carvalho, Daniel D., Dagli, Maria L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069004/ https://www.ncbi.nlm.nih.gov/pubmed/24959746 http://dx.doi.org/10.1371/journal.pone.0099484 |
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