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Additive effects of cilnidipine, an L-/N-type calcium channel blocker, and an angiotensin II receptor blocker on reducing cardiorenal damage in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes mellitus

Cilnidipine (Cil), which is an L-/N-type calcium channel blocker (CCB), has been known to provide renal protection by decreasing the activity of the sympathetic nervous system (SNS) and the renin–angiotensin system. In this study, we compared the effects of the combination of Cil and amlodipine (Aml...

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Detalles Bibliográficos
Autores principales: Mori, Yutaka, Aritomi, Shizuka, Niinuma, Kazumi, Nakamura, Tarou, Matsuura, Kenichi, Yokoyama, Junichi, Utsunomiya, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069052/
https://www.ncbi.nlm.nih.gov/pubmed/24970998
http://dx.doi.org/10.2147/DDDT.S47441