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Additive effects of cilnidipine, an L-/N-type calcium channel blocker, and an angiotensin II receptor blocker on reducing cardiorenal damage in Otsuka Long-Evans Tokushima Fatty rats with type 2 diabetes mellitus
Cilnidipine (Cil), which is an L-/N-type calcium channel blocker (CCB), has been known to provide renal protection by decreasing the activity of the sympathetic nervous system (SNS) and the renin–angiotensin system. In this study, we compared the effects of the combination of Cil and amlodipine (Aml...
Autores principales: | Mori, Yutaka, Aritomi, Shizuka, Niinuma, Kazumi, Nakamura, Tarou, Matsuura, Kenichi, Yokoyama, Junichi, Utsunomiya, Kazunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069052/ https://www.ncbi.nlm.nih.gov/pubmed/24970998 http://dx.doi.org/10.2147/DDDT.S47441 |
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